PDOX Fluorescent Imaging
Advanced fluorescent-based visualization tools enable scientists to observe tumor behavior in mouse models in real-time.
Our PDOX® visualization tools enable the scientist to clearly see the following:
- Real-time metastasis, tumor growth and progression;
- Angiogenesis, which is the formation of new blood vessels;
- Interactions of cancer cells with stromal cells, which control cancer cell growth and metastasis
- All types of agents, small molecules, proteins can be evaluated.
AngioMouse® fluorescent imaging technology
We have utilized multicolored fluorescent proteins to develop imaging models of tumor angiogenesis. Intra-vital and non-invasive imaging can visualize angiogenic capillaries at both primary and metastatic sites. Color-coded imaging allows visualization of cancer cells expressing one color fluorescent protein interacting with its blood vessels expressing a different color fluorescent protein. This model is highly valuable for discovery and evaluation of anti-angiogense agents.
StromaMouse™ fluorescent imaging technology
StromaMouse models express one or more color of fluorescent protein in stromal cells and cancer cells express a different color fluorescent protein. This model enables study of the Tumor Micro Environment (TME) and is ideal for discovery and evaluation of anti-stromal therapeutics.
To learn more about AC PDOX fluorescent imaging, reach out to us at email@example.com.